Bioactive Small Molecules
Cayman Chemical 3 4MethylendIoxyNbenzylca 5mg
A substituted cathinone that is structurally analogous to methylone, a narcotic which is regulated in the United States; intended for research and forensic applications
Cayman Chemical 3methylaPyrrolIdInobutIoph 5mg
An isomer of 4-methyl-α-PBP, having the methyl group attached at the 3 position of the phenyl ring, instead of the 4 position; intended for forensic and research applications
Medchemexpress LLC Biotin-PEG4-alkyne | 1458576-00-5 | MFCD22380755 | 99.7% | 457.58 g/mol | C21H35N3O6S | 5 MG
Biotin-PEG4-alkyne is a biotin-labeled polyethylene glycol (PEG4) linker with a terminal alkyne designed for copper-catalyzed azide-alkyne cycloaddition (CuAAC). It enables efficient biotinylation and affinity tagging of azide-containing molecules for pull-downs, imaging, or PROTAC assembly, offering good solubility and high chemical purity for biochemical applications.
- Terminal alkyne for CuAAC click chemistry.
- PEG4 spacer to improve solubility and reduce steric hindrance.
- Biotin handle for strong streptavidin/avidin affinity capture.
- High purity suitable for analytical and preparative workflows.
- Suitable for bioconjugation, labeling, and PROTAC linker assembly.
Medchemexpress LLC Camptothecin-20S-O-p 5mg | 194414-69-2 | 404.42 g/mol | C23H20N2O5 | 5 MG
Camptothecin-20(S)-O-propionate (CZ48) is the C20-propionate ester prodrug of camptothecin. It is described as a potent anticancer agent that acts by stabilizing topoisomerase I-DNA covalent complexes, impairing DNA religation and leading to cell death. Supplied for laboratory research in solid and solution forms for in vitro and in vivo studies.
- Prodrug of camptothecin with the C20 propionate modification.
- Topoisomerase I inhibitor mechanism of action.
- High reported purity suitable for research applications.
- Available as small solid quantities and as a DMSO solution for dosing or assay preparation.
- Intended for research use only; not for human therapeutic use.
Medchemexpress LLC Octyl-a-ketoglutarat 1mg | 876150-14-0 | 1 MG
Octyl-α-ketoglutarate is a cell-permeable ester derivative of α-ketoglutarate used in biochemical and cell biology research to increase intracellular α-ketoglutarate and modulate α-ketoglutarate-dependent enzymes such as prolyl hydroxylases. Molecular formula C13H22O5; molecular weight 258.31 g/mol. Supplied as a solid powder; follow the supplier datasheet for storage and handling.
- Cell-permeable α-ketoglutarate ester.
- Increases intracellular α-ketoglutarate levels.
- Used to study HIF regulation and prolyl hydroxylase activity.
- Supplied as a solid; follow the datasheet for storage and handling.
Medchemexpress LLC Inositol nicotinate | 6556-11-2 | 99.0% | 100 MG
Analytical standard of inositol nicotinate intended for research and analytical applications. Supplied as a solid reference material with high purity for method development, quantitative assays, and pharmacological research. Commonly used in HPLC, GC, and MS, and in studies of vasodilation.
- Analytical standard for HPLC, GC, and MS.
- High purity suitable for quantitative assays.
- Available in multiple pack sizes, including 100 MG.
- Intended for method development and validation.
- Solid form compatible with common laboratory solvents and protocols.
![Medchemexpress LLC 4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1206711-16-1 | >98.0% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231466.png-250.jpg)
Medchemexpress LLC 4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1206711-16-1 | >98.0% | 5 MG
DMH-1 is a small-molecule inhibitor of bone morphogenetic protein (BMP) type I receptors used in research to probe BMP/TGF-β signaling pathways. It provides potent, selective inhibition of ALK family kinases and is supplied as a high-purity analytical standard.
- Selective BMP type I receptor inhibitor with low-nanomolar activity.
- Reported IC50s: ALK1 27 nM; ALK2 107.9 nM; ALK3 <5 nM; ALK6 47.6 nM.
- Molecular formula C24H20N4O and molecular weight 380.44 g/mol.
- Purity ≥98% (HPLC).
- CAS number 1206711-16-1 for substance identification.
Medchemexpress LLC Ly2389575 hydrochloride | 885104-09-6 | MFCD28133385 | 99.9% | 438.58 | C15H16BrCl3N4 | 25 MG
LY2389575 hydrochloride is a research-only small molecule that acts as a selective, non-competitive negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3). It is used to probe mGlu3 pharmacology and related pathways, including effects on Mrc1 levels and amyloid beta-related toxicity in preclinical studies.
- Selective non-competitive mGlu3 negative allosteric modulator with reported IC50 ≈ 190 nM.
- High reported purity suitable for biochemical and cellular assays.
- Available in small milligram quantities and solution formats for assay flexibility.
- Stable under recommended storage conditions for extended sample retention.
- Useful for studies of receptor modulation, signaling, and amyloid beta interactions.
Apexbio Technology LLC Entinostat inhibits HDAC1 and HDAC3 but not HDAC8 209783-80-2. MFCD08272435
Entinostat inhibits HDAC1 and HDAC3 but not HDAC8 209783-80-2. MFCD08272435
Medchemexpress LLC Insulin Receptor Antibody (YA3666) | 100 UL
Insulin Receptor Antibody (YA3666) is a laboratory chemical designed for research use. It is supplied as a liquid and has predicted and observed molecular weights.
- Host: Mouse
- Reactivity: Human, Mouse, Monkey
- Clonality: YA3666
- SwissProt ID: P06213
- Gene ID: 3643
- Application: WB, ICC/IF, FC, ELISA
- Dilution ratio: WB: 1:500-1:2000; ICC/IF: 1:50-1:200; FC: 1:200-1:400; ELISA: 1:10000
- Formulation: Supplied in PBS with 0.05% sodium azide
- Storage: Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
![Medchemexpress LLC N-[3-(4-cyanophenyl)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide | 353235-01-5 | 99.7% | 377.46 g/mol | C21H19N3O2S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241269.png-250.jpg)
Medchemexpress LLC N-[3-(4-cyanophenyl)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide | 353235-01-5 | 99.7% | 377.46 g/mol | C21H19N3O2S | 5 MG
CBiPES is a small-molecule research compound that acts as a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 2 (mGlu2). It is intended for in vitro and preclinical research applications, and is supplied with analytical data confirming identity and high purity.
Medchemexpress LLC HY-122181B 5mg Medchemexpress, OTS186935 (hydrochloride) CAS:0 Purity:>98%
Medchemexpress, HY-122181B 5mg OTS186935 (hydrochloride) CAS:0 OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochloride regulates the production of γ-H2AX in cancer cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Reserpine 50mg 50-55-5
Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Ibudilast 25mg 50847-11-5 KC-404, AV411, MN166
Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities. *For Research & Development use only. Product is not intended for drug, household, or human consumption.